Mystery of Biphasic Defibrillation Waveform Efficacy
نویسندگان
چکیده
منابع مشابه
Electrode system influence on biphasic waveform defibrillation efficacy in humans.
BACKGROUND Several clinical studies have demonstrated a general superiority of biphasic waveform defibrillation compared with monophasic waveform defibrillation using epicardial lead systems. To test the breadth of utility of biphasic waveforms in humans, a prospective, randomized evaluation of defibrillation efficacy of monophasic and single capacitor biphasic waveform pulses was performed for...
متن کاملA prospective randomized evaluation of biphasic versus monophasic waveform pulses on defibrillation efficacy in humans.
Biphasic waveforms have been suggested as a superior waveform for ventricular defibrillation. To test this premise, a prospective randomized intraoperative evaluation of defibrillation efficacy of monophasic and biphasic waveform pulses was performed in 22 survivors of out of hospital ventricular fibrillation who were undergoing cardiac surgery for implantation of an automatic defibrillator. Th...
متن کاملThe biphasic mystery: why a biphasic shock is more effective than a monophasic shock for defibrillation.
We demonstrate that a biphasic shock is more effective than a monophasic shock at eliminating reentrant electrical activity in an ionic model of cardiac ventricular electrical activity. This effectiveness results from early hyperpolarization that enhances the recovery of sodium inactivation, thereby enabling earlier activation of recovering cells. The effect can be seen easily in a model of a s...
متن کاملAscending-ramp biphasic waveform has a lower defibrillation threshold and releases less troponin I than a truncated exponential biphasic waveform.
BACKGROUND We tested the hypothesis that the shape of the shock waveform affects not only the defibrillation threshold but also the amount of cardiac damage. METHODS AND RESULTS Defibrillation thresholds were determined for 11 waveforms-3 ascending-ramp waveforms, 3 descending-ramp waveforms, 3 rectilinear first-phase biphasic waveforms, a Gurvich waveform, and a truncated exponential biphasi...
متن کاملA comparison of biphasic and monophasic waveform defibrillation after prolonged ventricular fibrillation.
STUDY OBJECTIVE To compare the effects of biphasic defibrillation waveforms and conventional monophasic defibrillation waveforms on the success of initial defibrillation, postresuscitation myocardial function, and duration of survival after prolonged duration of untreated ventricular fibrillation (VF), including the effects of epinephrine. DESIGN Prospective, randomized, animal study. SETTI...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2008
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2008.05.041